Primers & Probes
Tube for PCR mix
Chlamydia trachomatis is a species of Gram-negative bacteria and obligate intracellular parasite in eukaryotic cells. C. trachomatis infection is one of the most common bacterial sexually transmitted infections in Europe. In women, Chlamydia trachomatis is responsible for a number of infections, including cervicitis, salpingitis, and endometritis, and may further develop into pelvic inflammatory disease (PID). Untreated Chlamydia can lead to severe consequences, particularly in pregnant women by putting their newborn at risk of infection (such as conjunctivitis, pharyngitis, and pneumonia). At least 70% of CT infections in women are asymptomatic. Chlamydia trachomatis infections in men are usually symptomatic, often presenting as urethral discharge or pain during urination (dysuria). C. trachomatis is responsible for urethritis and proctitis (or rectal infection). Occasionally, the infection spreads to the upper genital tract, leading to epididymitis or prostatitis.
Neisseria gonorrhoeae is a species of Gram-negative diplococci bacteria causing gonorrhea, a serious public health issue (52,995 cases were reported from 28 EU countries). Neisseria gonorrhoeae is sexually transmitted, most frequently infecting the uterus, cervix, vagina, anal-rectal region, oropharynx, and conjunctiva. Symptoms in men are often severe, usually manifesting as acute urethritis. Half of infected women are asymptomatic, whereas the clinical signs in those with symptoms are usually non-specific. Most infections of the oropharynx and anal-rectal region are asymptomatic in both men and women. If left untreated or if treatment fails, gonorrhea can spread locally and, in rare cases, systemically, leading to a number of serious complications. Women have an increased risk of developing complications such as PID, tubal infertility, and ectopic pregnancy due to diagnosis delays. In pregnant women, gonorrheal infections can affect the course of pregnancy. Newborn may also become infected during childbirth, resulting most commonly in ophthalmia with bilateral, purulent discharge, which may lead to blindness.
S-DiaCTNGTM is a trusted and easy-to-use molecular diagnostic CE-IVD kit allowing the qualitative detection of Chlamydia trachomatis and Neisseria gonorrhoeae by real-time PCR in clinical specimens (male and female urine and vaginal swabs) from patients potentially infected by these bacteria.