Mycoplasma genitalium is a small pathogenic bacterium which infects epithelial cells of the urinary and genital tracts. M. genitalium is an emerging sexually transmitted infection occuring during unprotected sexual intercourse. Mycoplasma genitalium is associated with notable reproductive tract syndromes such as cervicitis, pelvic inflammatory disease and infertility. Mycoplasma genitalium has been strongly associated with urethritis in both men and women and with cervicitis in women. Among Mycoplasma genitalium infected men, symptomatic urethritis is more common than asymptomatic urethritis. Owing to the slow cell replication and fastidious growth requirements, culture is impossible to use in clinical practice. Polymerase chain reaction (PCR) is currently the method of choice for detection.
Trichomonas vaginalis is an anaerobic flagellated protozoan. The parasitic microorganism is the causative agent of trichomoniasis, and is the most common pathogenic protozoan infection of humans in industrialized countries. Trichomonas vaginalis is sexually transmitted via skin-to-skin contact with an infected individual. Infection rates between men and women are the same with women showing symptoms while infections in men are usually asymptomatic. Complications may also occur in women (preterm delivery, low birth weight, and increased mortality as well as predisposing to HIV infection) and men (symptomatic urethritis and prostatitis).
S-DiaMGTVTM is a trusted and easy-to-use molecular diagnostic CE-IVD kit allowing the qualitative detection and the differentiation by real-time PCR of Mycoplasma genitalium and Trichomonas vaginalis in clinical specimens (male and female urine, urogenital swabs in Abbott®, Cobas® and Amplicor transport medium) from patients potentially infected by these pathogens.