Mycobacterium tuberculosis

R-DiaTub™

Mycobacterium tuberculosis is a pathogenic bacterial species in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882, Mycobacterium tuberculosis has an unusual, waxy coating that makes the cells impervious to Gram staining, reason why M. tuberculosis can appear either Gram-negative or Gram-positive. Primarily a pathogen of the mammalian respiratory system, M. tuberculosis infects the lungs and can also affect the central nervous system, the lymphatic system, the circulatory system, the genitourinary system, the gastrointestinal system, bones, joints, and even the skin. Other mycobacteria such as Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti also cause tuberculosis, but these species are less common.

R-DiaTub^TM is a trusted and easy-to-use molecular diagnostic CE-IVD kit designed to qualitatively detect Mycobacterium tuberculosis complex in biological samples (collected from patients showing symptoms related to its pathogen, by using real-time PCR .

• Validation

  DOUBLE-DYE PROBE & PRIMERS
  Targeted pathogens	Emission	Targeted genes	Volume
  Mycobacterium tuberculosis	FAM 520 nm	Insertion sequence (IS) 6110	250 µL

  EXTRACTION METHODS
  	Sputum	Nasopharyngeal swabs/washes	Bronchoalveolar Lavage
  NucleiSENS® EasyMAG® System (BioMérieux)
  MagNA Pure 96 System (Roche)
  QIAmp® DNA Mini Kit (Qiagen)
  QIAsymphony (Qiagen)

  Recommended
  Suitable

  PCR instruments
  Roche	ABI	Bio-Rad	Qiagen
  LC 480	7500 Fast	CFX96	Rotor-Gene
  LC 2.0		DX

  Recommended
  Suitable
• Documents

  SDS	DDGR-70-L100	SDS-DDGR-70-EN-v01-Mycobacterium-tuberculosis V01	EN	Download
  SDS	DDGR-70-L100	SDS-DDGR-70-FR-v01-Mycobacterium-tuberculosis V01	FR	Download

  CoA	DDGR-70-L100	08005G		Download
  CoA	DDGR-70-L100	01006K	2017-02-10	Download
  CoA	DDGR-70-L100	03008F	2018-08-14	Download