Human respiratory syncytial virus (HRSV) is an enveloped negative-sense RNA virus of the family Paramyxoviridae that causes respiratory tract infections. HRSV is a major cause of lower respiratory tract infections and hospital visits during infancy and childhood.
Human metapneumovirus (HMPV) is a negative single-stranded RNA virus of the family Pneumoviridae. Compared with respiratory syncytial virus, infection with human metapneumovirus tends to occur in slightly older children and to produce disease that is less severe. Co-infection with both viruses can occur, and is generally associated with worse disease. It seems that transmission occurs by contact with contaminated secretions, via droplet, aerosol, or fomite vectors. There is seasonal variation to Metapneumovirus infection, with most cases occurring in winter and early spring, a pattern that is similar to that of respiratory syncytial virus. About 5 to 10 percent of respiratory infections in children leading to hospitalization appear to be caused by Metapneumovirus, while the corresponding adult rates are not clear.
R-DiaResTM is a trusted and easy-to-use molecular diagnostic CE-IVD kit allowing the qualitative detection by real-time PCR of human Metapneumovirus and human respiratory syncytial virus in clinical specimens (nasopharyngeal swabs in GLY Medium) from patients potentially infected by these viruses.