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Human metapneumovirus, Human respiratory syncytial virus

R-DiaRes™

R-DiaRes
DDGR-46-L100
Probes & Primers
H2O
Positive control
Negative control
100 TESTS
Internal control suggested
DRIC™
Cy5
DiaInhib™
DR Cy5

Human respiratory syncytial virus (HRSV) is an enveloped negative-sense RNA virus of the family Paramyxoviridae that causes respiratory tract infections. HRSV is a major cause of lower respiratory tract infections and hospital visits during infancy and childhood.

Human metapneumovirus (HMPV) is a negative single-stranded RNA virus of the family Pneumoviridae. Compared with respiratory syncytial virus, infection with human metapneumovirus tends to occur in slightly older children and to produce disease that is less severe. Co-infection with both viruses can occur, and is generally associated with worse disease. It seems that transmission occurs by contact with contaminated secretions, via droplet, aerosol, or fomite vectors. There is seasonal variation to Metapneumovirus infection, with most cases occurring in winter and early spring, a pattern that is similar to that of respiratory syncytial virus. About 5 to 10 percent of respiratory infections in children leading to hospitalization appear to be caused by Metapneumovirus, while the corresponding adult rates are not clear.

R-DiaResTM is a trusted and easy-to-use molecular diagnostic CE-IVD kit allowing the qualitative detection by real-time PCR of human Metapneumovirus and human respiratory syncytial virus in clinical specimens (nasopharyngeal swabs in GLY Medium) from patients potentially infected by these viruses.

  • Validation
    DOUBLE-DYE PROBE & PRIMERS
    Targeted pathogens Emission Targeted genes Volume
    Human metapneumovirus FAM 520 nm Nucleoprotein gene (NP) 250 µL
    Human respiratory syncytial virus Yellow dye 549 nm Nucleoprotein gene (NP) 250 µL
    EXTRACTION METHODS
    Sputum Nasopharyngeal
    swabs/washes
    Bronchoalveolar
    Lavage
    NucleiSENS® EasyMAG® System (BioMérieux)
    MagNA Pure 96 System (Roche)
    QIAsymphony (Qiagen)
    Recommended
    Suitable
    PCR instruments
    Roche ABI Bio-Rad Qiagen
    LC 480 7500 Fast CFX96 Rotor-Gene
    Flow DX
    Recommended
    Suitable
  • Documents
    SDS-DDGR-46-EN-v01-Human-Respiratory-Syncytial-Virus-Human-Metapneumovirus en Download
    SDS-DDGR-46-FR-v01-Virus-respiratoire-syncytial-humain-Metapneumovirus-humain fr Download
    R-DiaRes_04006B  Download
    R-DiaRes_15115C_prolonge  Download
  • Publications

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