Mycobacterium tuberculosis Complex is a pathogenic bacterial species in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882, Mycobacterium tuberculosis has an unusual, waxy coating that makes the cells impervious to Gram staining, reason why M. tuberculosis can appear either Gram-negative or Gram-positive. Primarily a pathogen of the mammalian respiratory system, M. tuberculosis infects the lungs and can also affect the central nervous system, the lymphatic system, the circulatory system, the genitourinary system, the gastrointestinal system, bones, joints, and even the skin. Other mycobacteria such as Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canetti, Mycobacterium microti also cause tuberculosis, but these species are less common.
R-DiaMTBComplexTM is a trusted and easy-to-use molecular diagnostic CE-IVD kit validated on geneLEAD VIII designed to qualitatively detect Mycobacterium tuberculosis complex in biological samples (collected from patients showing symptoms related to its pathogen, by using real-time PCR .