Human parainfluenza viruses (HPIV) are a group of four distinct single-stranded RNA viruses belonging to the Paramyxoviridae family. HPIVs consist of serotypes HPIV-1, HPIV-2, HPIV-3 and HPIV-4, belonging to two different genera: Respirovirus (HPIV-1, HPIV-3) and Rubulavirus (HPIV-2, HPIV-4). Most transmission have been linked to close contact, especially in nosocomial infections. HPIV-1 and 2 have been demonstrated to be the principal causative agents behind croup which is a viral disease of the upper airway. HPIV-3 has been closely associated with bronchiolitis and pneumonia and principally targets those aged less 1 year. HPIV-4 remains infrequently detected. All of these viruses spread readily within hospitals and can cause outbreaks in nurseries and pediatric wards. HPIVs remain the second main cause of hospitalisation in children under 5 years of age suffering from a respiratory illness.
R-DiaHPIVTM is a trusted and easy-to-use molecular diagnostic CE-IVD kit allowing the qualitative detection by real-time PCR of human parainfluenza virus 1, 2, 3 and 4 in clinical specimens (nasopharyngeal swabs in GLY Medium) from patients potentially infected by these viruses.
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