Neisseria meningitidis (Serogroup A, B, C W135 & Y)

M-DiaSero™

Neisseria meningitidis is a Gram-negative bacterium that can cause meningitis and other forms of meningococcal diseases such as meningococcemia, a life-threatening sepsis. Neisseria meningitidis is thus responsible for considerable mortality all over the world. Most disease-causing Neisseira meningitidis strains belong to serogroups B and C in Europe, North & South America and Australia. It initially produces general symptoms like fatigue, fever, and headache and can rapidly progress to neck stiffness, coma and death in 10% of cases. 

M-DiaSero^TM is a trusted and easy-to-use molecular diagnostic CE-IVD kit designed to qualitatively detect Neisseria meningitidis and serogroups A, B, C, W135 & Y in biological samples (cerebrospinal fluid or whole blood) collected from potentially infected patients using real-time PCR.

• Validation

  DOUBLE-DYE PROBE & PRIMERS
  Targeted pathogens	Emission	Targeted genes	Volume
  Neisseria meningitidis	FAM 520 nm	ctrA	100 µL
  Serogroup A	FAM 520 nm	sacB	100 µL
  Serogroup B	FAM 520 nm	siaD	100 µL
  Serogroup C	FAM 520 nm	siaD	100 µL
  Serogroup W135	FAM 520 nm	synG	100 µL
  Serogroup Y	FAM 520 nm	synF	100 µL

  EXTRACTION METHODS
  	Whole Blood	Cerebrospinal fluid	Swabs
  NucleiSENS® EasyMAG® System (BioMérieux)
  MagNA Pure 96 System (Roche)
  QIAmp® DNA Mini Kit (Qiagen)

  Recommended
  Suitable

  PCR instruments
  Roche	ABI	Bio-Rad	Qiagen
  LC 480	7500 Fast	CFX96	Rotor-Gene
  LC 2.0		DX

  Recommended
  Suitable
• Documents

  SDS-DDGM-20-EN-v02-M-DiaSero en	Download
  SDS-DDGM-20-FR-v02-M-DiaSero fr	Download

  CoA_DDGM-20-L040_02006I	Download
  M-DiaSero_2016J21I	Download
  CoA_DDGM-20-L040_03007F 2017-09-18	Download

• Publications