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Norovirus I / II and Rotavirus

G-DiaNotaV™ (Available Soon)

MTB GL 8
DPSG-10-L080

Probes & Primers
H2O
Positive control
Negative control
RNA extraction control virus
RNA master mix

80 TESTS
Internal control included
DiaControlRNA
Cy5

Norovirus is a nonenveloped RNA virus that causes approximately 90% of epidemic non-bacterial outbreaks of gastroenteritis around the world, and may be responsible for 50% of all foodborne outbreaks of gastroenteritis in the US. Norovirus affects people of all ages. The viruses are transmitted by faecally contaminated food or water, by person-to-person contact and via aerosolization of the virus and subsequent contamination of surfaces. The main symptom is acute gastroenteritis that develops between 12 and 48 hours after exposure. The disease is usually self-limiting, and characterized by nausea, forceful vomiting, watery diarrhea, and abdominal pain, and in some cases, loss of taste. General lethargy, weakness, muscle aches, headache, coughs, and low-grade fever may occur.

Rotavirus is a genus of double-stranded RNA virus in the family Reoviridae. Rotavirus is the most common cause of severe diarrhea among infants and young children, and is one of several viruses that cause infections often called stomach flu, despite having no relation to influenza. By the age of five, nearly every child in the world has been infected with rotavirus at least once. However, with each infection, immunity is developed, subsequent infections are less severe, and adults are rarely affected. There are five species of this virus, referred to as A, B, C, D, and E. Rotavirus A, the most common, causes more than 90% of infections in humans.

G-DiaNotaVTM will be validated on geneLEAD VIII allowing the qualitative detection and differentiation of Norovirus (genogroups I and II) and Rotavirus by real-time PCR in clinical specimens (liquid and soft stools) from patients potentially presenting with gastro-enteric symptoms.

  • Validation
    DOUBLE-DYE PROBE & PRIMERS
    Targeted pathogens Emission Targeted genes Volume
    Novovirus I FAM 520 nm RdRp/Capsid junction 250 µL
    Novovirus II Yellow dye 549 nm NKP2 250 µL
    Rotavirus Texas Red 603 nm NSP3 250 µL
    EIC RNA Cy5 662 nm tcdB (enterotoxin B) 250 µL
    EXTRACTION METHODS
    Stool
    geneLEAD VIII

    Recommended
    Suitable

    PCR instruments
    PSS
    geneLEAD VIII

    Recommended
    Suitable

  • Documents

Upcoming events

  • AACC
    Aug 6-Aug 8, 2019
    Anaheim, CA USA
  • EMMD
    Oct 9-Oct 11, 2019
    Noordwijk, the Netherlands
  • RICAI
    Dec 16-Dec 17, 2019
    Paris, France
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