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Norovirus I and II, Rotavirus

G-DiaNota™

G-DiaNota
DDGG-10-L100
Probes & Primers
H2O
Positive control
Negative control
RNA extraction control virus
RNA master mix
100 TESTS
Internal control included
DiaControlRNA
Cy5

Norovirus is a nonenveloped RNA virus that causes approximately 90% of epidemic non-bacterial outbreaks of gastroenteritis around the world, and may be responsible for 50% of all foodborne outbreaks of gastroenteritis in the US. Norovirus affects people of all ages. The viruses are transmitted by faecally contaminated food or water, by person-to-person contact and via aerosolization of the virus and subsequent contamination of surfaces. The main symptom is acute gastroenteritis that develops between 12 and 48 hours after exposure. The disease is usually self-limiting, and characterized by nausea, forceful vomiting, watery diarrhea, and abdominal pain, and in some cases, loss of taste. General lethargy, weakness, muscle aches, headache, coughs, and low-grade fever may occur.

Rotavirus is a genus of double-stranded RNA virus in the family Reoviridae. Rotavirus is the most common cause of severe diarrhea among infants and young children, and is one of several viruses that cause infections often called stomach flu, despite having no relation to influenza. By the age of five, nearly every child in the world has been infected with rotavirus at least once. However, with each infection, immunity is developed, subsequent infections are less severe, and adults are rarely affected. There are five species of this virus, referred to as A, B, C, D, and E. Rotavirus A, the most common, causes more than 90% of infections in humans.

G-DiaNotaTM is a trusted and easy-to-use molecular diagnostic CE-IVD kit allowing the qualitative detection and differentiation of Norovirus (genogroups I and II) and Rotavirus by real-time PCR in clinical specimens (liquid and soft stools) from patients potentially presenting with gastro-enteric symptoms.

   

Effective as of January 1, 2017, Diagenode S.A. obtains the rights to the patents covering the detection of Norwalk-like Virus I and II:US patent No. 7,202,032, EP patent No. 1329522, US patent No. 7,351,819 and EP patent No. 1329523 under licensing agreement.

  • Validation
    DOUBLE-DYE PROBE & PRIMERS
    Targeted pathogens Emission Targeted genes Volume
    Novovirus I FAM 520 nm RdRp/Capsid junction 250 µL
    Novovirus II Yellow dye 549 nm NKP2 250 µL
    Rotavirus Texas Red 603 nm NSP3 250 µL
    EIC RNA Cy5 662 nm tcdB (enterotoxin B) 250 µL
    EXTRACTION METHODS
    Stool
    NucleiSENS® EasyMAG® System (BioMérieux)
    MagNA Pure 96 System (Roche)
    QIAsymphony (Qiagen)
    Recommended
    Suitable
    PCR instruments
    Roche ABI Bio-Rad Qiagen
    LC 480 7500 Fast CFX96 Rotor-Gene
    DX
    Recommended
    Suitable
  • Documents
    SDS-DDGG-10-FR-v01-G-diaNota fr Download
    SDS-DDGG-10-EN-v01-G-diaNota en Download
    CoA_G-DiaNota_04005L  Download
    DDGG-10-L100_05006E  Download
    CoA_DDGG-10-L100_06006L 2017-03-06 Download
  • Publications

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